
We thank Fermentek for the information, the free Nonactin granted for our project, and most of all, the moral support |
Link friends 17dmag 7aad actinomycin alfatoxin-b1 aflatoxin-b2 aflatoxin-g1 aflatoxin-g2 aflatoxin-m1 aflatoxin-m2 anisomycin ascomycin Blukher Bukharin dybenko frinovsky geldanamycin k252a k252b kt5720 kt5823 leptomycin Link-Exchange mithramycin mitomycin nonactin Ochratoxin parthenolide Snorring staurosporine tinnitus trichostatin tukhachevsky verruculogen vomitoxin wortmannin yakir yegorov yezhov zearalenone
Here come some links to top-rated hrefs, such as Microsoft, wikipedia, Google and Yahoo :google, microsoft, yahoo, wikipedia
Now come links to these of fermentek product pages, that are needy : .the homepage of fermentek, FK506 or tacrolimus, products of Fermentek: staurosporine, K252A, aflatoxin, Sirolimus (Rapamycin) And other link beggars: Tinnitus. about some guys that had tinnitus | 14: Arch Biochem Biophys. 1992 May 1;294(2):418-26. Calorimetry of tetraether lipids from Thermoplasma acidophilum: incorporation of alamethicin, melittin, valinomycin, and nonactin.
Freisleben HJ, Blocher D, Ring K.
Gustav-Embden-Zentrum der Biologischen Chemie, Johann Wolfgang Goethe-Universitat, Frankfurt/Main, Germany.
The development and application of model membrane systems on the basis of tetraether lipids from Thermoplasma acidophilum has been proposed. In this respect incorporation of membrane proteins and ionophores is indispensable and is demonstrated in the case of alamethicin, melittin, nonactin, and valinomycin by calorimetry. Dipalmitoylphosphatidylcholine (DPPC) and dihexadecylmaltosylglycerol (DHMG) were chosen for comparison. Melittin and alamethicin prove to broaden the lipid phase transition and to reduce the melting temperature Tm and enthalpy change (delta H) of the main phospholipid from T. acidophilum (MPL) and DPPC. The decrease in Tm, however, is more pronounced in DPPC than in MPL. Valinomycin shows only a marginal effect on the temperature and width of the transition; delta H is reduced in MPL and remains constant in DPPC and DHMG. With nonactin the phase transition of DPPC is quenched, and delta H and the half-height width are increased. DHMG is affected to a lesser extent and MPL only marginally. The four ionophores exhibit different modulation of the phase transition behavior of the various lipids as expected from their varying molecular structures. Thus, the integral membrane protein alamethicin, the peripheral protein melittin, valinomycin, and nonactin interact primarily with lipid head groups and are readily incorporated into the tetraether lipid structures.
PMID: 1567197
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